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All files can be downloaded by clicking on the link. When this results in the file being opened directly, downloading can be done by right-clicking the link and choosing "Save as..".
Excel 5.0/97 (Dutch version) DAS28 calculator and DAS calculator
Excel 2000 worksheet with all all available DAS and DAS28 calculators (with both ESR and CRP)
Javascript webcalculator for all DAS and DAS28 with both ESR and CRP: DASculators
Ready-to-use Word 5.0/97 DAS28 form
The different DAS formulas that have been developed and validated are mentioned below:
DAS(4) = 0.54*sqrt(RAI) + 0.065*(swollen44) + 0.33*Ln(ESR) + 0.0072*GH
DAS(3) = 0.54*sqrt(RAI) + 0.065*(swollen44) + 0.33*Ln(ESR) + 0.22
DAS-4(crp) = 0.54*sqrt(RAI)+ 0.065*SJC44 + 0.17*ln(CRP+1) + 0.0072*GH + 0.45
DAS-3(crp) = 0.54*sqrt(RAI)+ 0.065*SJC44 + 0.17*ln(CRP+1) + 0.65
High disease activity >3.7, low disease activity <2.4, remission <1.6
DAS28(4) = (0.56*sqrt(t28) + 0.28*sqrt(sw28) + 0.70*Ln(ESR) + 0.014*GH
DAS28(3) = [0.56*sqrt(t28) + 0.28*sqrt(sw28) + 0.70*Ln(ESR)]*1.08 + 0.16
DAS28-CRP(4) = 0.56*sqrt(TJC28) + 0.28*sqrt(SJC28) + 0.36*ln(CRP+1) + 0.014*GH + 0.96
DAS28-CRP(3) = [0.56*sqrt(TJC28) + 0.28*sqrt(SJC28) + 0.36*ln(CRP+1)] * 1.10 + 1.15
High disease activity >5.1, low disease activity <3.2, remission <2.6
DAS28 = (1.072)*DAS) + 0.938
RAI = number of painfull joints calculated with the Ritchie Articular Index
swollen = number of swollen joints from 44 joints
t28 = number of painfull joints from 28 joints
sw28 = number of swollen joints from 28 joints
ESR = erythrocyte sedimentation rate in mm/first hour
GH = general health or patient's global assessment of disease activity on a 100 mm VAS
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